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Peptide record

TPDB72354

Neurotoxin standard
61 amino acids
Basic Information
3D PDB MODEL
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TPDB72354
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 61-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKAIIFLFAVLTVVAIIIPIISGEPNAGPLAASIDLKQIMEKVKPDLLKMLDDIKAKIQQG
Physicochemical Analysis
C305H518N72O81S3
RCHWY
I
6586.08
9.48
7
6
34
+1
9.09
0.731
145.57
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
7
A
0
R
1
N
4
D
0
C
2
E
3
Q
3
G
0
H
11
I
7
L
7
K
3
M
2
F
4
P
2
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 7 R: 0 N: 1 D: 4 C: 0 E: 2 Q: 3 G: 3 H: 0 I: 11 L: 7 K: 7 M: 3 F: 2 P: 4 S: 2 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
61
C305H518N72O81S3
6586.08
9.48
+1
9.09
0.731
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Toxin that causes a rapid and irreversible paralysis when intrathoracically injected into insects (blowflies). Does not cause spontaneous nocifensive behaviors by intraplantar injection in mice. {ECO:0000269|PubMed:38110035}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Pogonomyrmex maricopa (Maricopa harvester ant)
Neurotoxin
Toxin that causes a rapid and irreversible paralysis when intrathoracically injected into insects (blowflies). Does not cause spontaneous nocifensive behaviors by intraplantar injection in mice..
Myrmicitoxin(1)-Pm5a (MYRTX(1)-Pm5a)
insect
Formicidae venom clade 2 family
Evidence at protein level
Amidation Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:38110035}.
Additional Detail Fields 7 fields
Amidation Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Formicidae venom clade 2 family
Myrmicitoxin(1)-Pm5a (MYRTX(1)-Pm5a)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:38110035}.
insect