TPDB

3D PDB MODEL

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TPDB ID TPDB72347

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 120-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKLLYFFVVITVLVAVAAALPAKTEEQIAAEENQLVEDLVQYAGTRLTRKRATRCSKKLGEKCNYHCECCGATVACSTVYVGGKETNFCSDKTSNNGALNTVGQGLNVVSNGLSAFQCWG

FASTA

>TPDB72347|Neurotoxin|length=120
MKLLYFFVVITVLVAVAAALPAKTEEQIAAEENQLVEDLVQYAGTRLTRKRATRCSKKLGEKCNYHCECCGATVACSTVYVGGKETNFCSDKTSNNGALNTVGQGLNVVSNGLSAFQCWG

Formula C560H900N156O174S9

Absent Amino Acids

Common Amino Acids AV

Mass 12890.79

PI 7.84

Basic Residues 13

Acidic Residues 10

Hydrophobic Residues 49

Net Charge +2

Boman Index 19.37

Hydrophobicity 0.046

Aliphatic Index 84.50

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 11960

Absorbance 280nm 92.78

Polar Residues 41

number

13

A

4

R

8

N

2

D

8

C

8

E

5

Q

10

G

1

H

2

I

11

L

8

K

1

M

4

F

1

P

6

S

10

T

1

W

4

Y

13

V

Amino Acid Distribution

A: 13 R: 4 N: 8 D: 2 C: 8 E: 8 Q: 5 G: 10 H: 1 I: 2 L: 11 K: 8 M: 1 F: 4 P: 1 S: 6 T: 10 W: 1 Y: 4 V: 13

Length

120

Formula

C560H900N156O174S9

Mass

12890.79

PI

7.84

Net Charge

+2

Boman Index

19.37

Hydrophobicity

0.046

Evidence 1 Activity

Source & Reference

Database Source NA