TPDB

3D PDB MODEL

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TPDB ID TPDB72330

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 244-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MGKELLTFSDLTWLDSSPDTVRSAFTREYGTTPDGIALNSEGYFGYHSPPITEQYGRPCYKQTGETKITLQELGPSTDAVLGNSTAVNRGDSSIDLTVSVEGKWSDSTSWSTSTETGVKMSSEFEVEGAFKMGGEFSLTLSVGKSGSSSVEKTSTSSVQVTVPPRSKVVVSMVGIMKKEKVFFEVPVTVDGSFGANFPSTVQGHYFWFMDARSCLNKTSGVIKGTIDHANVFDVSVEVGPSEPL

FASTA

>TPDB72330|Neurotoxin|length=244
MGKELLTFSDLTWLDSSPDTVRSAFTREYGTTPDGIALNSEGYFGYHSPPITEQYGRPCYKQTGETKITLQELGPSTDAVLGNSTAVNRGDSSIDLTVSVEGKWSDSTSWSTSTETGVKMSSEFEVEGAFKMGGEFSLTLSVGKSGSSSVEKTSTSSVQVTVPPRSKVVVSMVGIMKKEKVFFEVPVTVDGSFGANFPSTVQGHYFWFMDARSCLNKTSGVIKGTIDHANVFDVSVEVGPSEPL

Formula C1158H1793N297O380S8

Absent Amino Acids

Common Amino Acids S

Mass 26212.22

PI 4.68

Basic Residues 23

Acidic Residues 29

Hydrophobic Residues 83

Net Charge -9

Boman Index 51.23

Hydrophobicity -0.244

Aliphatic Index 66.15

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 31065

Absorbance 280nm 118.51

Polar Residues 79

number

8

A

6

R

6

N

12

D

2

C

17

E

5

Q

24

G

3

H

7

I

13

L

14

K

6

M

13

F

12

P

35

S

25

T

4

W

6

Y

26

V

Amino Acid Distribution

A: 8 R: 6 N: 6 D: 12 C: 2 E: 17 Q: 5 G: 24 H: 3 I: 7 L: 13 K: 14 M: 6 F: 13 P: 12 S: 35 T: 25 W: 4 Y: 6 V: 26

Length

244

Formula

C1158H1793N297O380S8

Mass

26212.22

PI

4.68

Net Charge

-9

Boman Index

51.23

Hydrophobicity

-0.244

Evidence 1 Activity

Source & Reference

Database Source NA