TPDB

3D PDB MODEL

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TPDB ID TPDB72303

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 194-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MSLVPVVVEQTNRGERSYDIYSRLLKDRIIMLSEEVNDTTASLIVAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICVGMAASMGAFLLAAGAKGKRYALPNSEVMIHQPLGGFRGQATDIGIHAERILKMKKKLNTILSDRTGKPLEQVELDTERDHFLSAEEAKEYGLIDEVIDKKK

FASTA

>TPDB72303|Neurotoxin|length=194
MSLVPVVVEQTNRGERSYDIYSRLLKDRIIMLSEEVNDTTASLIVAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICVGMAASMGAFLLAAGAKGKRYALPNSEVMIHQPLGGFRGQATDIGIHAERILKMKKKLNTILSDRTGKPLEQVELDTERDHFLSAEEAKEYGLIDEVIDKKK

Formula C949H1542N254O294S9

Absent Amino Acids W

Common Amino Acids L

Mass 21502.75

PI 5.13

Basic Residues 27

Acidic Residues 29

Hydrophobic Residues 82

Net Charge -6

Boman Index 53.04

Hydrophobicity -0.189

Aliphatic Index 98.56

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 10430

Absorbance 280nm 48.51

Polar Residues 42

number

15

A

9

R

5

N

14

D

1

C

15

E

6

Q

14

G

4

H

17

I

20

L

14

K

8

M

4

F

7

P

13

S

10

T

0

W

7

Y

11

V

Amino Acid Distribution

A: 15 R: 9 N: 5 D: 14 C: 1 E: 15 Q: 6 G: 14 H: 4 I: 17 L: 20 K: 14 M: 8 F: 4 P: 7 S: 13 T: 10 W: 0 Y: 7 V: 11

Length

194

Formula

C949H1542N254O294S9

Mass

21502.75

PI

5.13

Net Charge

-6

Boman Index

53.04

Hydrophobicity

-0.189

Evidence 1 Activity

Source & Reference

Database Source NA