TPDB

3D PDB MODEL

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TPDB ID TPDB72290

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 78-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MRFLHFLIVAVLLASFMESGAMPRNPKKKRGWDTPAPCRYCQWNGPQCCVYYCSSCNYEEAREEGHYVSSHLLERQGR

FASTA

>TPDB72290|Neurotoxin|length=78
MRFLHFLIVAVLLASFMESGAMPRNPKKKRGWDTPAPCRYCQWNGPQCCVYYCSSCNYEEAREEGHYVSSHLLERQGR

Formula C400H606N116O111S9

Absent Amino Acids

Common Amino Acids R

Mass 9104.46

PI 8.29

Basic Residues 13

Acidic Residues 7

Hydrophobic Residues 29

Net Charge +3

Boman Index 12.93

Hydrophobicity -0.512

Aliphatic Index 56.28

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 18825

Absorbance 280nm 206.77

Polar Residues 24

number

5

A

7

R

3

N

1

D

6

C

6

E

3

Q

5

G

3

H

1

I

6

L

3

K

3

M

3

F

5

P

6

S

1

T

2

W

5

Y

4

V

Amino Acid Distribution

A: 5 R: 7 N: 3 D: 1 C: 6 E: 6 Q: 3 G: 5 H: 3 I: 1 L: 6 K: 3 M: 3 F: 3 P: 5 S: 6 T: 1 W: 2 Y: 5 V: 4

Length

78

Formula

C400H606N116O111S9

Mass

9104.46

PI

8.29

Net Charge

+3

Boman Index

12.93

Hydrophobicity

-0.512

Evidence 1 Activity

Source & Reference

Database Source NA