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Peptide record

TPDB72277

Neurotoxin standard
114 amino acids
Basic Information
3D PDB MODEL
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TPDB72277
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 114-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
TSCETHQICGRKIIYRDGTTNTQEIDYCRCSGDTDCPKDDVNEISFVDWSYWEVSYYTCLTQAGNYHYCNEGAAVQPGAGPIIYRQNNVEHPYKMNCRCNPCWINKARCCTPGT
Physicochemical Analysis
C556H833N159O179S13
C
13025.47
5.39
13
13
33
-3
22.15
-0.705
47.89
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
30660
235.39
50
Residue Composition
number
5
A
6
R
9
N
7
D
12
C
6
E
5
Q
8
G
3
H
8
I
1
L
4
K
1
M
1
F
6
P
5
S
10
T
3
W
9
Y
5
V
Amino Acid Distribution
A: 5 R: 6 N: 9 D: 7 C: 12 E: 6 Q: 5 G: 8 H: 3 I: 8 L: 1 K: 4 M: 1 F: 1 P: 6 S: 5 T: 10 W: 3 Y: 9 V: 5
Chemical Descriptors
114
C556H833N159O179S13
13025.47
5.39
-3
22.15
-0.705
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Acts as a neurotoxin by inhibiting an ion channel. {ECO:0000250}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Iotyrris olangoensis (Sea snail) (Lophiotoma olangoensis)
Neurotoxin Ion channel impairing toxin
Acts as a neurotoxin by inhibiting an ion channel..
Turripeptide OL22 (Turripeptide OL78)
other
Evidence at transcript level
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 6 fields
Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Toxin
Neurotoxin Ion channel impairing toxin
Evidence at transcript level
Turripeptide OL22 (Turripeptide OL78)
TISSUE SPECIFICITY: Expressed by the venom duct.
other