TPDB

3D PDB MODEL

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TPDB ID TPDB72224

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 123-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAGAGAAEEKTEFDVVLADAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK

FASTA

>TPDB72224|Neurotoxin|length=123
MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAGAGAAEEKTEFDVVLADAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK

Formula C556H936N144O183S3

Absent Amino Acids HWY

Common Amino Acids A

Mass 12662.58

PI 4.53

Basic Residues 17

Acidic Residues 25

Hydrophobic Residues 58

Net Charge -8

Boman Index 53.19

Hydrophobicity 0.019

Aliphatic Index 101.71

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 10

number

25

A

1

R

1

N

4

D

1

C

21

E

1

Q

11

G

0

H

6

I

10

L

16

K

2

M

2

F

2

P

3

S

4

T

0

W

0

Y

13

V

Amino Acid Distribution

A: 25 R: 1 N: 1 D: 4 C: 1 E: 21 Q: 1 G: 11 H: 0 I: 6 L: 10 K: 16 M: 2 F: 2 P: 2 S: 3 T: 4 W: 0 Y: 0 V: 13

Length

123

Formula

C556H936N144O183S3

Mass

12662.58

PI

4.53

Net Charge

-8

Boman Index

53.19

Hydrophobicity

0.019

Evidence 1 Activity

Source & Reference

Database Source NA