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Peptide record

TPDB72222

Neurotoxin standard
66 amino acids
Basic Information
3D PDB MODEL
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TPDB72222
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 66-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MMYCLPVVCILLLLIPSSATFVVESRLEKDQAQSFTGDAWKRVSPIHEMIQRSQCCAVKKNCCHVG
Physicochemical Analysis
C324H527N89O91S9
V
7413.83
8.02
9
5
28
+2
10.03
0.291
95.91
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7365
99.34
20
Residue Composition
number
4
A
3
R
1
N
2
D
6
C
3
E
4
Q
2
G
2
H
4
I
6
L
4
K
3
M
2
F
3
P
6
S
2
T
1
W
1
Y
7
V
Amino Acid Distribution
A: 4 R: 3 N: 1 D: 2 C: 6 E: 3 Q: 4 G: 2 H: 2 I: 4 L: 6 K: 4 M: 3 F: 2 P: 3 S: 6 T: 2 W: 1 Y: 1 V: 7
Chemical Descriptors
66
C324H527N89O91S9
7413.83
8.02
+2
10.03
0.291
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target. Possibly targets ion channels. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Californiconus californicus (California cone) (Conus californicus)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target. Possibly targets ion channels..
Conotoxin Cal5.2
cone snail
Conotoxin T superfamily
Evidence at protein level
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
Additional Detail Fields 7 fields
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin T superfamily
Conotoxin Cal5.2
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
cone snail