TPDB

3D PDB MODEL

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TPDB ID TPDB72211

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 179-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MYEYLDRRYALALYEVAEENNKVDEYLRDLKEVVNIIKNSEDICKILKHPEINTSRKKEIFTELFKDKVDDKILSFLLVLIEKDRILYLEEKLKEMEKIYLEKNNMILANIKTVIPLLKEEREELIEKLGNKYNKKIILEEEIDKSIIGGVYVRVGDDVLDGTLSTRLKDIKKMMLKRE

FASTA

>TPDB72211|Neurotoxin|length=179
MYEYLDRRYALALYEVAEENNKVDEYLRDLKEVVNIIKNSEDICKILKHPEINTSRKKEIFTELFKDKVDDKILSFLLVLIEKDRILYLEEKLKEMEKIYLEKNNMILANIKTVIPLLKEEREELIEKLGNKYNKKIILEEEIDKSIIGGVYVRVGDDVLDGTLSTRLKDIKKMMLKRE

Formula C961H1590N244O285S6

Absent Amino Acids QW

Common Amino Acids K

Mass 21315.02

PI 5.36

Basic Residues 36

Acidic Residues 38

Hydrophobic Residues 77

Net Charge -3

Boman Index 73.63

Hydrophobicity -0.440

Aliphatic Index 118.10

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13410

Absorbance 280nm 62.91

Polar Residues 30

number

4

A

9

R

10

N

13

D

1

C

25

E

0

Q

5

G

1

H

20

I

25

L

26

K

5

M

3

F

2

P

5

S

5

T

0

W

9

Y

11

V

Amino Acid Distribution

A: 4 R: 9 N: 10 D: 13 C: 1 E: 25 Q: 0 G: 5 H: 1 I: 20 L: 25 K: 26 M: 5 F: 3 P: 2 S: 5 T: 5 W: 0 Y: 9 V: 11

Length

179

Formula

C961H1590N244O285S6

Mass

21315.02

PI

5.36

Net Charge

-3

Boman Index

73.63

Hydrophobicity

-0.440

Evidence 1 Activity

Source & Reference

Database Source NA