TPDB

3D PDB MODEL

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TPDB ID TPDB72147

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 134-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKLAVVFLLTTVVFTLAQSQCENCADLQCNSTVHCCLVSTVRLPRWKREISRCGRLAIRRWRCEEPNSNGIYNRNCPCVPGLECREFRRGRRICLPEQSSTSTSSTQGPITSSTVTTQSEATTETETTTAAEGK

FASTA

>TPDB72147|Neurotoxin|length=134
MKLAVVFLLTTVVFTLAQSQCENCADLQCNSTVHCCLVSTVRLPRWKREISRCGRLAIRRWRCEEPNSNGIYNRNCPCVPGLECREFRRGRRICLPEQSSTSTSSTQGPITSSTVTTQSEATTETETTTAAEGK

Formula C626H1031N195O203S12

Absent Amino Acids

Common Amino Acids T

Mass 14921.98

PI 8.24

Basic Residues 18

Acidic Residues 12

Hydrophobic Residues 38

Net Charge +5

Boman Index 33.08

Hydrophobicity -0.383

Aliphatic Index 68.36

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 13115

Absorbance 280nm 87.89

Polar Residues 55

number

7

A

14

R

6

N

1

D

11

C

11

E

6

Q

6

G

1

H

5

I

10

L

3

K

1

M

3

F

6

P

13

S

18

T

2

W

1

Y

9

V

Amino Acid Distribution

A: 7 R: 14 N: 6 D: 1 C: 11 E: 11 Q: 6 G: 6 H: 1 I: 5 L: 10 K: 3 M: 1 F: 3 P: 6 S: 13 T: 18 W: 2 Y: 1 V: 9

Length

134

Formula

C626H1031N195O203S12

Mass

14921.98

PI

8.24

Net Charge

+5

Boman Index

33.08

Hydrophobicity

-0.383

Evidence 1 Activity

Source & Reference

Database Source NA