TPDB

3D PDB MODEL

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TPDB ID TPDB72133

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 124-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

MKTMIAWLVLLTFAAALCFADEGLKQEHMNERKKSRFREDIPDEISEDLLLQEMEAMEAELLEKEMRMEENRNSREKRCLGEDISCGEKPGDLVRMPCCAKYECKETAGYWWYQKRFCVKKKSG

FASTA

>TPDB72133|Neurotoxin|length=124
MKTMIAWLVLLTFAAALCFADEGLKQEHMNERKKSRFREDIPDEISEDLLLQEMEAMEAELLEKEMRMEENRNSREKRCLGEDISCGEKPGDLVRMPCCAKYECKETAGYWWYQKRFCVKKKSG

Formula C633H1011N175O192S15

Absent Amino Acids

Common Amino Acids E

Mass 14625.95

PI 5.21

Basic Residues 23

Acidic Residues 25

Hydrophobic Residues 46

Net Charge -3

Boman Index 46.67

Hydrophobicity -0.698

Aliphatic Index 64.60

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 21345

Absorbance 280nm 145.94

Polar Residues 24

number

9

A

9

R

3

N

6

D

7

C

19

E

3

Q

6

G

1

H

4

I

12

L

13

K

8

M

4

F

3

P

5

S

3

T

3

W

3

Y

3

V

Amino Acid Distribution

A: 9 R: 9 N: 3 D: 6 C: 7 E: 19 Q: 3 G: 6 H: 1 I: 4 L: 12 K: 13 M: 8 F: 4 P: 3 S: 5 T: 3 W: 3 Y: 3 V: 3

Length

124

Formula

C633H1011N175O192S15

Mass

14625.95

PI

5.21

Net Charge

-3

Boman Index

46.67

Hydrophobicity

-0.698

Evidence 1 Activity

Source & Reference

Database Source NA