TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB72070

Activity

Neurotoxin

Activity_category_statistics

Toxicity and safety peptides

Database_Source

NTxPred2

Sequence_Type

standard

Has_Modification No

Description A 76-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.

Sequence

SFVFYLFTLITVVRAEEFILENEAEDIAPAVHGESGRECIGHRRSCKEDRNGCCRLYTCNCWYPTPGDQWCKCQLW

FASTA

>TPDB72070|Neurotoxin|length=76
SFVFYLFTLITVVRAEEFILENEAEDIAPAVHGESGRECIGHRRSCKEDRNGCCRLYTCNCWYPTPGDQWCKCQLW

Formula C390H584N108O114S8

Absent Amino Acids M

Common Amino Acids CE

Mass 8866.06

PI 5.07

Basic Residues 10

Acidic Residues 11

Hydrophobic Residues 27

Net Charge -3

Boman Index 14.13

Hydrophobicity -0.311

Aliphatic Index 66.71

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 21470

Absorbance 280nm 242.16

Polar Residues 23

number

4

A

6

R

3

N

3

D

8

C

8

E

2

Q

5

G

2

H

4

I

5

L

2

K

0

M

4

F

3

P

3

S

4

T

3

W

3

Y

4

V

Amino Acid Distribution

A: 4 R: 6 N: 3 D: 3 C: 8 E: 8 Q: 2 G: 5 H: 2 I: 4 L: 5 K: 2 M: 0 F: 4 P: 3 S: 3 T: 4 W: 3 Y: 3 V: 4

Length

76

Formula

C390H584N108O114S8

Mass

8866.06

PI

5.07

Net Charge

-3

Boman Index

14.13

Hydrophobicity

-0.311

Evidence 1 Activity

Source & Reference

Database Source NA