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Peptide record

TPDB72046

Neurotoxin standard
107 amino acids
Basic Information
3D PDB MODEL
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TPDB72046
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 107-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLFMFAAIIFTMASTTVRAEQCANNRKVCTWDGQGDTNCDCIGTACHEDDAHKVSVAGSAFYTCQPISAFRVCDGSEDVMDAGFSELYCRCSGGSYTISNGEVVCD
Physicochemical Analysis
C485H744N134O163S14
A
11508.88
4.26
9
14
40
-7
16.80
0.005
57.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
10595
92.06
37
Residue Composition
number
11
A
4
R
4
N
9
D
10
C
5
E
3
Q
9
G
2
H
5
I
2
L
3
K
4
M
6
F
1
P
9
S
8
T
1
W
3
Y
8
V
Amino Acid Distribution
A: 11 R: 4 N: 4 D: 9 C: 10 E: 5 Q: 3 G: 9 H: 2 I: 5 L: 2 K: 3 M: 4 F: 6 P: 1 S: 9 T: 8 W: 1 Y: 3 V: 8
Chemical Descriptors
107
C485H744N134O163S14
11508.88
4.26
-7
16.80
0.005
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Acts as a neurotoxin. {ECO:0000250}.

Target

proton-gated sodium channel / ASIC

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Conus caracteristicus (Characteristic cone)
Neurotoxin
Acts as a neurotoxin..
Putative conotoxin
cone snail
Evidence at transcript level
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct.
Additional Detail Fields 6 fields
Cleavage on pair of basic residues Disulfide bond Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at transcript level
Putative conotoxin
TISSUE SPECIFICITY: Expressed by the venom duct.
cone snail