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Peptide record

TPDB72018

Neurotoxin standard
68 amino acids
Basic Information
3D PDB MODEL
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TPDB72018
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 68-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLCVVIVLLMLAMPFNGGEASRFFNQHARSQRSGMKTRGIWCDPPCPKGETCRGGECSDEFNSDVGR
Physicochemical Analysis
C320H509N97O95S9
Y
G
7523.69
8.14
10
7
22
+2
14.21
-0.325
55.88
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5750
76.43
17
Residue Composition
number
3
A
6
R
3
N
3
D
5
C
4
E
2
Q
8
G
1
H
2
I
4
L
3
K
4
M
4
F
4
P
5
S
2
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 6 N: 3 D: 3 C: 5 E: 4 Q: 2 G: 8 H: 1 I: 2 L: 4 K: 3 M: 4 F: 4 P: 4 S: 5 T: 2 W: 1 Y: 0 V: 4
Chemical Descriptors
68
C320H509N97O95S9
7523.69
8.14
+2
14.21
-0.325
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: Probable neurotoxin with unknown target. Possibly targets ion channels. {ECO:0000305}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Californiconus californicus (California cone) (Conus californicus)
Neurotoxin Ion channel impairing toxin
Probable neurotoxin with unknown target. Possibly targets ion channels..
Conotoxin Cal14.13a (Conotoxin Cal14.1a)
cone snail
Evidence at protein level
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
Additional Detail Fields 6 fields
Amidation Disulfide bond Ion channel impairing toxin Neurotoxin Secreted Signal Toxin
Neurotoxin Ion channel impairing toxin
Evidence at protein level
Conotoxin Cal14.13a (Conotoxin Cal14.1a)
TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|PubMed:21172372}.
cone snail