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Peptide record

TPDB72003

Neurotoxin standard
66 amino acids
Basic Information
3D PDB MODEL
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TPDB72003
Neurotoxin
Toxicity and safety peptides
NTxPred2
standard
No
A 66-aa standard natural neurotoxin peptide sequence curated from NTxPred2, with an available 3D structural model.
Sequence
MKLSFLSLAFAVIFVMAIMYAPQVEAKASADADADADAAASADALAKASAGMLDRILGAVKGFMGS
Physicochemical Analysis
C296H476N74O89S5
NCHTW
A
6655.78
4.32
5
7
42
-2
2.17
0.767
99.55
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
22.39
8
Residue Composition
number
19
A
1
R
0
N
6
D
0
C
1
E
1
Q
4
G
0
H
3
I
6
L
4
K
5
M
4
F
1
P
6
S
0
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 19 R: 1 N: 0 D: 6 C: 0 E: 1 Q: 1 G: 4 H: 0 I: 3 L: 6 K: 4 M: 5 F: 4 P: 1 S: 6 T: 0 W: 0 Y: 1 V: 4
Chemical Descriptors
66
C296H476N74O89S5
6655.78
4.32
-2
2.17
0.767
Evidence Records 1 records
Evidence 1 Activity

Activity

Neurotoxin
FUNCTION: In vivo, this neurotoxin paralyzes about 50% of blowflies (L.caesar) one hour after intrathoracic injection, when tested at high doses (54 nmol/g). {ECO:0000269|PubMed:37888631}.

Source & Reference

NA
UniProtKB/Swiss-Prot Tox-Prot

Other

Tetramorium bicarinatum (Tramp ant)
Neurotoxin
In vivo, this neurotoxin paralyzes about 50% of blowflies (L.caesar) one hour after intrathoracic injection, when tested at high doses (54 nmol/g)..
U8-myrmicitoxin-Tb1a (U8-MYRTX-Tb1a)
insect
Formicidae venom precursor-01 superfamily
Evidence at protein level
Neurotoxin Secreted Signal Toxin
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:30149710}.
Additional Detail Fields 7 fields
Neurotoxin Secreted Signal Toxin
Neurotoxin
Evidence at protein level
Formicidae venom precursor-01 superfamily
U8-myrmicitoxin-Tb1a (U8-MYRTX-Tb1a)
TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|PubMed:30149710}.
insect