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Peptide record

TPDB71910

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB71910
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 9-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
WVPVDPNIE
Physicochemical Analysis
C50H73N11O15
ARCQGHLKMFSTY
PV
1068.19
3.01
0
2
4
-2
2.55
-0.189
107.78
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
514.89
1
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
1
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
9
C50H73N11O15
1068.19
3.01
-2
2.55
-0.189
1068.1764
1067.5270
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lorey S., Stockel-Maschek A., Faust J., Brandt W., Stiebitz B., Gorrell M. D., Kahne T., Mrestani-Klaus C., Wrenger S., Reinhold D., Ansorge S.,Neub
Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites. Eur. J. Biochem. 270, 2147–2156
2003
Journal

Other

9
Additional Detail Fields 1 fields
9