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Peptide record

TPDB71890

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB71890
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 2-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
WC
Physicochemical Analysis
C14H17N3O3S1
ARNDEQGHILKMFPSTYV
CW
307.37
5.33
0
0
1
-0
-2.09
0.800
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
1789.39
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
2
C14H17N3O3S1
307.37
5.33
-0
-2.09
0.800
307.3685
307.0987
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
420.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
In silico approaches to predict the potential of milk protein-derived peptides as dipeptidyl peptidase IV (DPP-IV) inhibitors. Peptides 57, 43-51, 2014
2014
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CS)C(=O)O InChI=1S/C14H17N3O3S/c15-10(13(18)17-12(7-21)14(19)20)5-8-6-16-11-4-2-1-3-9(8)11/h1-4,6,10,12,16,21H,5,7,15H2,(H,17,18)(H,19,20)/t10-,12-/m0/s1 InChIKey=SMDQRGAERNMJJF-JQWIXIFHSA-N
Additional Detail Fields 1 fields
2