Peptide record

TPDB71868

Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB71868
Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 2-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
VC
Physicochemical Analysis
C8H16N2O3S1
ARNDEQGHILKMFPSTWY
CV
220.29
5.33
0
0
1
-0
-0.17
3.350
145.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
2
C8H16N2O3S1
220.29
5.33
-0
-0.17
3.350
220.2897
220.0878
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
5413.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Neves A. C., Harnedy P. A., O’Keeffe M. B., FitzGerald R. J.
Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities. Food Chem., 218, 396–405, 2017
2017
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)O InChI=1S/C8H16N2O3S/c1-4(2)6(9)7(11)10-5(3-14)8(12)13/h4-6,14H,3,9H2,1-2H3,(H,10,11)(H,12,13)/t5-,6-/m0/s1 InChIKey=WPSXZFTVLIAPCN-WDSKDSINSA-N Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides
Additional Detail Fields 1 fields
2