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Peptide record

TPDB71866

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB71866
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV pep-lab Peptipedia
standard
No
A 7-aa standard-residue idppiv peptide sequence curated from iDPPIV, pep-lab, and Peptipedia, with an available 3D structural model.
Sequence
TTAGLLE
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C30H53N7O12
RNDCQHIKMFPSWYV
LT
703.79
3.29
0
1
3
-1
-0.09
0.586
125.71
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
7 reviewed residue count
C30H53N7O12 sequence-only estimate (linear, free termini)
703.79 sequence-only estimate (linear, free termini)
3.29 sequence-only estimate (linear, free termini)
-1 sequence-only estimate (linear, free termini)
-0.09 sequence-only estimate (linear, free termini)
0.586 sequence-only estimate (linear, free termini)
703.7794 Activity
703.3739 Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
de Souza Rocha T., Hernandez L. M. R., Chang Y. K., González de Mejía E.
Impact of germination and enzymatic hydrolysis of cowpea bean (Vigna unguiculata) on the generation of peptides capable of inhibiting dipeptidyl peptidase IV. Food Research International 64, 799-809
2014
Journal

Other

7
Additional Detail Fields 1 fields
7