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Peptide record

TPDB71807

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB71807
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 4-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
PPPP
Physicochemical Analysis
C20H30N4O5
ARNDCEQGHILKMFSTWYV
P
406.48
6.02
0
0
0
-0
1.80
-1.600
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
4
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 4 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C20H30N4O5
406.48
6.02
-0
1.80
-1.600
406.4748
406.2209
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Harada M., Fukasawa K. M., Fukasawa K., Nagatsu T.
Inhibitory action of proline-containing peptides on Xaa-Pro-dipeptidylaminopeptidase. Biochim. Biophys. Acta, 705, 288-290
1982
Journal

Other

4
BIOPEP database of bioactive peptides SMILES: N1[C@H](C(=O)N2[C@H](C(=O)N3[C@H](C(=O)N4[C@H](C(=O)O)CCC4)CCC3)CCC2)CCC1 InChI=1S/C20H30N4O5/c25-17(13-5-1-9-21-13)22-10-2-6-14(22)18(26)23-11-3-7-15(23)19(27)24-12-4-8-16(24)20(28)29/h13-16,21H,1-12H2,(H,28,29)/t13-,14-,15-,16-/m0/s1 InChIKey: CBNLHHITRUAXOE-VGWMRTNUSA-N
Additional Detail Fields 1 fields
4