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Peptide record

TPDB71775

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB71775
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 9-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
MWPVDPNIE
Physicochemical Analysis
C50H73N11O15S1
ARCQGHLKFSTY
P
1100.25
3.01
0
2
4
-2
2.25
-0.444
75.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
499.88
1
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
1
E
0
Q
0
G
0
H
1
I
0
L
0
K
1
M
0
F
2
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 1 F: 0 P: 2 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
9
C50H73N11O15S1
1100.25
3.01
-2
2.25
-0.444
1100.2425
1099.4991
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
2.20 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Faust J., Fuchs P., Wrenger S., Reinhold D., Stöckel-Maschek A., Kähne T., Ansorge S., Neubert K.
Dipeptidyl peptidase IV inhibitors with the N-terminal MXP sequence: Structure-activity-relationships. Adv. Exp. Med. Biol., 524, 175-179
2003
Journal

Other

9
Additional Detail Fields 1 fields
9