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Peptide record

TPDB71774

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB71774
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 9-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
MWPTSSSTK
Physicochemical Analysis
C44H69N11O15S1
ARNDCEQGHILFYV
S
1024.16
10.10
1
0
2
+1
0.03
-0.922
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
537.03
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
1
M
0
F
1
P
3
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 1 S: 3 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C44H69N11O15S1
1024.16
10.10
+1
0.03
-0.922
1024.1467
1023.4679
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lorey S., Stockel-Maschek A., Faust J., Brandt W., Stiebitz B., Gorrell M. D., Kahne T., Mrestani-Klaus C., Wrenger S., Reinhold D., Ansorge S.,Neub
Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites. Eur. J. Biochem. 270, 2147–2156
2003
Journal

Other

9
Additional Detail Fields 1 fields
9