Back to search

Peptide record

TPDB71764

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB71764
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 2-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
MR
Physicochemical Analysis
C11H23N5O3S1
ANDCEQGHILKFPSTWYV
RM
305.40
11.05
1
0
1
+1
0.58
-1.300
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C11H23N5O3S1
305.40
11.05
+1
0.58
-1.300
305.3972
305.1517
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI=1S/C11H23N5O3S/c1-20-6-4-7(12)9(17)16-8(10(18)19)3-2-5-15-11(13)14/h7-8H,2-6,12H2,1H3,(H,16,17)(H,18,19)(H4,13,14,15)/t7-,8-/m0/s1 InChIKey=UASDAHIAHBRZQV-YUMQZZPRSA-N Inhibitor of Dipeptidyl peptidase III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.003) according to the BIOPEP-UWM database of bioactive peptides (ID:9479) Information concerning Dipeptidyl peptidase IV (DPP IV) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: S09.003)
Additional Detail Fields 1 fields
2