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Peptide record

TPDB71740

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB71740
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV pep-lab Peptipedia
standard
No
A 13-aa standard natural idppiv peptide sequence curated from iDPPIV, pep-lab, and Peptipedia, with an available 3D structural model.
Sequence
MAPTSSSTKKTQL
Physicochemical Analysis
C57H102N16O21S1
RNDCEGHIFWYV
ST
1379.59
10.60
2
0
3
+2
2.86
-0.762
37.69
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
2
K
1
M
0
F
1
P
3
S
3
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 2 M: 1 F: 0 P: 1 S: 3 T: 3 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C57H102N16O21S1
1379.59
10.60
+2
2.86
-0.762
1379.5764
1378.7102
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lorey S., Stockel-Maschek A., Faust J., Brandt W., Stiebitz B., Gorrell M. D., Kahne T., Mrestani-Klaus C., Wrenger S., Reinhold D., Ansorge S.,Neub
Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites. Eur. J. Biochem. 270, 2147–2156
2003
Journal

Other

13
Additional Detail Fields 1 fields
13