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Peptide record

TPDB71711

Dipeptidyl peptidase IV inhibitor iDPPIV standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB71711
Dipeptidyl peptidase IV inhibitor
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 3-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
LPQ
Physicochemical Analysis
C16H28N4O5
ARNDCEGHIKMFSTWYV
QLP
356.42
6.02
0
0
1
-0
0.47
-0.433
130.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C16H28N4O5
356.42
6.02
-0
0.47
-0.433
356.4162
356.2053
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
82.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Uenishi H., Kabuki T., Seto Y., Serizawa A., Nakajima H.
Isolation and identification of casein-derived dipeptidyl-pepdiase-4 (DPP-4)-inhibitory peptide LPQNIPPL from gouda-type cheese and its effect on plasma glucose in rats. Int Dairy J., 2012 22: 24-30.
2012
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O InChI=1S/C16H28N4O5/c1-9(2)8-10(17)15(23)20-7-3-4-12(20)14(22)19-11(16(24)25)5-6-13(18)21/h9-12H,3-8,17H2,1-2H3,(H2,18,21)(H,19,22)(H,24,25)/t10-,11-,12-/m0/s1 InChIKey: XWEVVRRSIOBJOO-SRVKXCTJSA-N
Additional Detail Fields 1 fields
3