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Peptide record

TPDB71672

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB71672
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 3-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
IPM
Physicochemical Analysis
C16H29N3O4S1
ARNDCEQGHLKFSTWYV
IMP
359.48
6.02
0
0
2
-0
-0.09
1.600
130.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C16H29N3O4S1
359.48
6.02
-0
-0.09
1.600
359.4841
359.1872
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
69.50 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., FitzGerald R. J.
Structure activity relationship modelling of milk protein-derived peptides with dipeptidyl peptidase IV (DPP-IV) inhibitory activity. Peptides, 2016, 79, 1-7.
2016
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCSC)C(O)=O InChI=1S/C16H29N3O4S/c1-4-10(2)13(17)15(21)19-8-5-6-12(19)14(20)18-11(16(22)23)7-9-24-3/h10-13H,4-9,17H2,1-3H3,(H,18,20)(H,22,23)/t10-,11-,12-,13-/m0/s1 InChIKey: CZWANIQKACCEKW-CYDGBPFRSA-N
Additional Detail Fields 1 fields
3