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Peptide record

TPDB71662

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB71662
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 4-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
ILAP
Physicochemical Analysis
C20H36N4O5
RNDCEQGHKMFSTWYV
AILP
412.53
6.02
0
0
3
-0
-0.59
2.125
220.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C20H36N4O5
412.53
6.02
-0
-0.59
2.125
412.5222
412.2677
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
43.40 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Harnedy P. A., O’Keeffe M. B., FitzGerald R. J.
Purification and identification of dipeptidyl peptidase (DPP) IV inhibitory peptides from the macroalga Palmaria palmata. Food Chemistry 172, 400-406, 2015
2015
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C20H36N4O5/c1-6-12(4)16(21)18(26)23-14(10-11(2)3)17(25)22-13(5)19(27)24-9-7-8-15(24)20(28)29/h11-16H,6-10,21H2,1-5H3,(H,22,25)(H,23,26)(H,28,29)/t12-,13-,14-,15-,16-/m0/s1 InChIKey= QPWJPUVZYLAXCK-QXKUPLGCSA-N
Additional Detail Fields 1 fields
4