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Peptide record

TPDB71658

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Umami iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB71658
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Umami iDPPIV
Cardiometabolic peptides Food sensory peptides
Tastepeptides-Meta iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Umami and iDPPIV) peptide sequence curated from Tastepeptides-Meta, iDPPIV, and Peptipedia, with an available 3D structural model.
Sequence
IH
Physicochemical Analysis
C12H20N4O3
ARNDCEQGLKMFPSTWYV
HI
268.32
7.85
1
0
1
+0
0.65
0.650
195.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C12H20N4O3
268.32
7.85
+0
0.65
0.650
268.3114
268.1531
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)O)N InChI=1S/C12H20N4O3/c1-3-7(2)10(13)11(17)16-9(12(18)19)4-8-5-14-6-15-8/h5-7,9-10H,3-4,13H2,1-2H3,(H,14,15)(H,16,17)(H,18,19)/t7-,9-,10-/m0/s1 InChIKey=QNBYCZTZNOVDMI-HGNGGELXSA-N Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9497)
Additional Detail Fields 1 fields
2