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Peptide record

TPDB71633

Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB71633
Dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 4-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
GPAV
Physicochemical Analysis
C15H26N4O5
RNDCEQHILKMFSTWY
AGPV
342.40
6.02
0
0
2
-0
0.36
1.000
97.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C15H26N4O5
342.40
6.02
-0
0.36
1.000
342.3897
342.1897
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
245.15 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Neves A. C., Harnedy P. A., O’Keeffe M. B., FitzGerald R. J.
Bioactive peptides from Atlantic salmon (Salmo salar) with angiotensin converting enzyme and dipeptidyl peptidase IV inhibitory, and antioxidant activities. Food Chem., 218, 396–405, 2017
2017
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C(C)C)C(=O)O InChI=1S/C8H16N2O3S/c1-4(2)6(9)7(11)10-5(3-14)8(12)13/h4-6,14H,3,9H2,1-2H3,(H,10,11)(H,12,13)/t5-,6-/m0/s1 InChIKey=WPSXZFTVLIAPCN-WDSKDSINSA-N Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides
Additional Detail Fields 1 fields
4