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Peptide record

TPDB71631

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB71631
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 4-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
GPAE
Physicochemical Analysis
C15H24N4O7
RNDCQHILKMFSTWYV
AEGP
372.38
3.29
0
1
1
-1
2.31
-0.925
25.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C15H24N4O7
372.38
3.29
-1
2.31
-0.925
372.3727
372.1639
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
49.60 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Li-Chan E. C. Y., Huang S. L., Jao C. L., Ho K. P., Hsu K. C.
Peptides derived from atlantic salmon skin gelatin as dipeptidyl-peptidase IV inhibitors. J. Agric. Food Chem., 60, 973-978, 2012
2012
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O InChI=1S/C15H24N4O7/c1-8(13(23)18-9(15(25)26)4-5-12(21)22)17-14(24)10-3-2-6-19(10)11(20)7-16/h8-10H,2-7,16H2,1H3,(H,17,24)(H,18,23)(H,21,22)(H,25,26)/t8-,9-,10-/m0/s1 InChIKey: PUUMSPGMEPVNLS-GUBZILKMSA-N
Additional Detail Fields 1 fields
4