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Peptide record

TPDB71618

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB71618
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV Peptipedia
standard
No
A 4-aa standard natural idppiv peptide sequence curated from iDPPIV and Peptipedia, with an available 3D structural model.
Sequence
FLQP
Physicochemical Analysis
C25H37N5O6
ARNDCEGHIKMSTWYV
QLFP
503.60
6.02
0
0
2
-0
-0.66
0.375
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C25H37N5O6
503.60
6.02
-0
-0.66
0.375
503.5897
503.2735
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
65.30 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., FitzGerald R. J.
Inhibition of dipeptidyl peptidase IV (DPP-IV) by proline containing casein-derived peptides. J. Funct. Foods, 5, 1909-1917, 2013
2013
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C25H37N5O6/c1-15(2)13-19(29-22(32)17(26)14-16-7-4-3-5-8-16)23(33)28-18(10-11-21(27)31)24(34)30-12-6-9-20(30)25(35)36/h3-5,7-8,15,17-20H,6,9-14,26H2,1-2H3,(H2,27,31)(H,28,33)(H,29,32)(H,35,36)/t17-,18-,19-,20-/m0/s1 InChIKey= YKQNVNONYGLMFH-MUGJNUQGSA-N
Additional Detail Fields 1 fields
4