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Peptide record

TPDB71585

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) iDPPIV standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB71585
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
iDPPIV
Cardiometabolic peptides
iDPPIV pep-lab Peptipedia
standard
No
A 7-aa standard natural idppiv peptide sequence curated from iDPPIV, pep-lab, and Peptipedia, with an available 3D structural model.
Sequence
APGPAGP
Physicochemical Analysis
C25H39N7O8
RNDCEQHILKMFSTWYV
P
565.63
6.02
0
0
2
-0
1.03
-0.286
28.57
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C25H39N7O8
565.63
6.02
-0
1.03
-0.286
565.6177
565.2851
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
105.44 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Zhang Y., Chen R., Chen X., Zeng Z., Ma H., Chen S.
Dipeptidyl peptidase IV-inhibitory peptides derived from silver carp (Hypophthalmichthys molitrix Val.) proteins. J. Agric. Food Chem., 64, 831-839, 2016
2016
Journal

Other

7
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C25H39N7O8/c1-14(26)24(38)32-11-4-6-16(32)22(36)28-13-19(33)30-9-3-7-17(30)23(37)29-15(2)21(35)27-12-20(34)31-10-5-8-18(31)25(39)40/h14-18H,3-13,26H2,1-2H3,(H,27,35)(H,28,36)(H,29,37)(H,39,40)/t14-,15-,16-,17-,18-/m0/s1 InChIKey= YLHGGIUFFQYKSL-ATIWLJMLSA-N
Additional Detail Fields 1 fields
7