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Peptide record

TPDB67206

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB67206
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
MAMGL
Physicochemical Analysis
C21H39N5O6S2
RNDCEQHIKFPSTWYV
M
521.69
6.02
0
0
4
-0
-1.18
1.800
98.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
2
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 2 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C21H39N5O6S2
521.69
6.02
-0
-1.18
1.800
521.6949
521.2333
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
Ding L., Ma R., You H., Li J., Ge Q., Yu Z., Wang L.
Identification and characterization of dipeptidyl peptidase IV inhibitory peptides from wheat gluten proteins. Journal of Cereal Science, 103, 103396, 2022
2022
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)O InChI=1S/C21H39N5O6S2/c1-12(2)10-16(21(31)32)25-17(27)11-23-20(30)15(7-9-34-5)26-18(28)13(3)24-19(29)14(22)6-8-33-4/h12-16H,6-11,22H2,1-5H3,(H,23,30)(H,24,29)(H,25,27)(H,26,28)(H,31,32)/t13-,14-,15-,16-/m0/s1 InChIKey= DHZBYQKOONXGRW-VGWMRTNUSA-N
Additional Detail Fields 1 fields
5