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Peptide record

TPDB67023

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB67023
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IGL
Physicochemical Analysis
C14H27N3O4
ARNDCEQHKMFPSTWYV
GIL
301.39
6.02
0
0
2
-0
-0.86
2.633
260.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C14H27N3O4
301.39
6.02
-0
-0.86
2.633
301.3808
301.1995
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
2220.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
Carrera-Alvarado G., Toldrá F., Mora L.
DPP-IV Inhibitory Peptides GPF, IGL, and GGGW Obtained from Chicken Blood Hydrolysates. Int. J. Mol. Sci., 23 (22), 2022
2022
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)NCC(=O)N[C@@]([H])(CC(C)C)C(=O)O InChI= 1S/C14H27N3O4/c1-5-9(4)12(15)13(19)16-7-11(18)17-10(14(20)21)6-8(2)3/h8-10,12H,5-7,15H2,1-4H3,(H,16,19)(H,17,18)(H,20,21)/t9-,10-,12-/m0/s1 InChIKey= NYEYYMLUABXDMC-NHCYSSNCSA-N
Additional Detail Fields 1 fields
3