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Peptide record

TPDB66977

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66977
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 7-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GPVGPPG
Physicochemical Analysis
C26H41N7O8
ARNDCEQHILKMFSTWY
GP
579.65
6.02
0
0
1
-0
1.45
-0.257
41.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C26H41N7O8
579.65
6.02
-0
1.45
-0.257
579.6442
579.3007
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
He L., Wang X., Wang Y., Luo J., Zhao Y., Han G., Han L., Yu Q.
Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded cowhide collagen. Food Chemistry, 405, 134793, 2023
2023
Journal

Other

7
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)O InChI=1S/C26H41N7O8/c1-15(2)22(30-24(39)17-7-3-9-31(17)19(34)12-27)25(40)28-13-20(35)32-10-5-8-18(32)26(41)33-11-4-6-16(33)23(38)29-14-21(36)37/h15-18,22H,3-14,27H2,1-2H3,(H,28,40)(H,29,38)(H,30,39)(H,36,37)/t16-,17-,18-,22-/m0/s1 InChIKey= BXDJCQURUMWFJP-ORGXJRBJSA-N
Additional Detail Fields 1 fields
7