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Peptide record

TPDB66976

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66976
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GPVG
Physicochemical Analysis
C14H24N4O5
ARNDCEQHILKMFSTWY
G
328.37
6.02
0
0
1
-0
0.54
0.450
72.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C14H24N4O5
328.37
6.02
-0
0.54
0.450
328.3632
328.1741
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
He L., Wang X., Wang Y., Luo J., Zhao Y., Han G., Han L., Yu Q.
Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded cowhide collagen. Food Chemistry, 405, 134793, 2023
2023
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)O InChI=1S/C14H24N4O5/c1-8(2)12(14(23)16-7-11(20)21)17-13(22)9-4-3-5-18(9)10(19)6-15/h8-9,12H,3-7,15H2,1-2H3,(H,16,23)(H,17,22)(H,20,21)/t9-,12-/m0/s1 InChIKey= IZDUTASAHLIPQS-CABZTGNLSA-N
Additional Detail Fields 1 fields
4