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Peptide record

TPDB66974

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66974
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 6-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GPPGPT
Physicochemical Analysis
C23H36N6O8
ARNDCEQHILKMFSWYV
P
524.57
6.02
0
0
0
-0
1.51
-1.050
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C23H36N6O8
524.57
6.02
-0
1.51
-1.050
524.5659
524.2586
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
He L., Wang X., Wang Y., Luo J., Zhao Y., Han G., Han L., Yu Q.
Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded cowhide collagen. Food Chemistry, 405, 134793, 2023
2023
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O InChI=1S/C23H36N6O8/c1-13(30)19(23(36)37)26-21(34)15-6-2-8-27(15)18(32)12-25-20(33)14-5-3-10-29(14)22(35)16-7-4-9-28(16)17(31)11-24/h13-16,19,30H,2-12,24H2,1H3,(H,25,33)(H,26,34)(H,36,37)/t13-,14+,15+,16+,19+/m1/s1 InChIKey= ZXNJLDBAPCRBBZ-CUGJGTHOSA-N
Additional Detail Fields 1 fields
6