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Peptide record

TPDB66968

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB66968
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GPF
Physicochemical Analysis
C16H21N3O4
ARNDCEQHILKMSTWYV
GFP
319.36
6.02
0
0
1
-0
-0.67
0.267
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C16H21N3O4
319.36
6.02
-0
-0.67
0.267
319.3548
319.1527
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
940.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
Carrera-Alvarado G., Toldrá F., Mora L.
DPP-IV Inhibitory Peptides GPF, IGL, and GGGW Obtained from Chicken Blood Hydrolysates. Int. J. Mol. Sci., 23 (22), 2022
2022
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O InChI= 1S/C16H21N3O4/c17-10-14(20)19-8-4-7-13(19)15(21)18-12(16(22)23)9-11-5-2-1-3-6-11/h1-3,5-6,12-13H,4,7-10,17H2,(H,18,21)(H,22,23)/t12-,13-/m0/s1 InChIKey= IXHQLZIWBCQBLQ-STQMWFEESA-N
Additional Detail Fields 1 fields
3