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Peptide record

TPDB66881

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66881
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FGPGP
Physicochemical Analysis
C23H31N5O6
ARNDCEQHILKMSTWYV
GP
473.53
6.02
0
0
1
-0
-0.21
-0.240
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C23H31N5O6
473.53
6.02
-0
-0.21
-0.240
473.5209
473.2267
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
He L., Wang X., Wang Y., Luo J., Zhao Y., Han G., Han L., Yu Q.
Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded cowhide collagen. Food Chemistry, 405, 134793, 2023
2023
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C23H31N5O6/c24-16(12-15-6-2-1-3-7-15)21(31)25-13-19(29)27-10-4-8-17(27)22(32)26-14-20(30)28-11-5-9-18(28)23(33)34/h1-3,6-7,16-18H,4-5,8-14,24H2,(H,25,31)(H,26,32)(H,33,34)/t16-,17-,18-/m0/s1 InChIKey= JZIASZGKIKKSJS-BZSNNMDCSA-N
Additional Detail Fields 1 fields
5