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Peptide record

TPDB66765

Dipeptidyl peptidase IV inhibitor Antidiabetic standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66765
Dipeptidyl peptidase IV inhibitor
Antidiabetic
Cardiometabolic peptides
Peptipedia
standard
No
A 6-aa standard natural antidiabetic peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
APGGAP
Physicochemical Analysis
C20H32N6O7
RNDCEQHILKMFSTWYV
AGP
468.51
6.02
0
0
2
-0
0.58
-0.067
33.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C20H32N6O7
468.51
6.02
-0
0.58
-0.067
468.5028
468.2325
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antidiabetic
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

NA
He L., Wang X., Wang Y., Luo J., Zhao Y., Han G., Han L., Yu Q.
Production and identification of dipeptidyl peptidase IV (DPP-IV) inhibitory peptides from discarded cowhide collagen. Food Chemistry, 405, 134793, 2023
2023
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C20H32N6O7/c1-11(21)18(30)25-7-3-5-13(25)17(29)23-9-15(27)22-10-16(28)24-12(2)19(31)26-8-4-6-14(26)20(32)33/h11-14H,3-10,21H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)(H,32,33)/t11-,12-,13-,14-/m0/s1 InChIKey= KFZDTJKNTFFGHK-XUXIUFHCSA-N
Additional Detail Fields 1 fields
6