Back to search

Peptide record

TPDB66710

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66710
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
YTFPFH
Physicochemical Analysis
C42H50N8O9
ARNDCEQGILKMSWV
F
810.91
7.77
1
0
3
+0
-1.65
-0.200
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
183.74
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
2
F
1
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 2 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
6
C42H50N8O9
810.91
7.77
+0
-1.65
-0.200
810.8926
810.3689
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
24.12 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Aiemratchanee P., Panyawechamontri K., Phaophu P., Reamtong O., Panbangred W.
In vitro antihypertensive activity of bioactive peptides derived from porcine blood corpuscle and plasma proteins. Int. J. Food Sci. Technol., 56, 2315–2324, 2021
2021
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H]([C@H](O)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CC5=C[N]([H])C=N5)C(=O)O InChI=1S/C42H50N8O9/c1-25(51)36(49-37(53)31(43)19-28-14-16-30(52)17-15-28)40(56)47-33(21-27-11-6-3-7-12-27)41(57)50-18-8-13-35(50)39(55)46-32(20-26-9-4-2-5-10-26)38(54)48-34(42(58)59)22-29-23-44-24-45-29/h2-7,9-12,14-17,23-25,31-36,51-52H,8,13,18-22,43H2,1H3,(H,44,45)(H,46,55)(H,47,56)(H,48,54)(H,49,53)(H,58,59)/t25-,31+,32+,33+,34+,35+,36+/m1/s1 InChIKey=JYTMWFNOBUFZLF-WAWHIKOHSA-N
Additional Detail Fields 1 fields
6