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Peptide record

TPDB66694

ACE inhibitor ACE inhibitors standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB66694
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
WMY
Physicochemical Analysis
C25H30N4O5S1
ARNDCEQGHILKFPSTV
MWY
498.60
5.94
0
0
3
-0
-3.02
-0.100
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
1401.93
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
1
M
0
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
3
C25H30N4O5S1
498.60
5.94
-0
-3.02
-0.100
498.5944
498.1930
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
550.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Xu Z., Wu C., Sun-Waterhouse D., Zhao T., Waterhouse G. I. N., Zhao M., Su G.
Identification of post-digestion angiotensin-I converting enzyme (ACE) inhibitory peptides from soybean protein Isolate: Their production conditions and in silico molecular docking with ACE. Food Chem., 345, 128855, 2021
2021
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)O InChI=1S/C25H30N4O5S/c1-35-11-10-21(24(32)29-22(25(33)34)12-15-6-8-17(30)9-7-15)28-23(31)19(26)13-16-14-27-20-5-3-2-4-18(16)20/h2-9,14,19,21-22,27,30H,10-13,26H2,1H3,(H,28,31)(H,29,32)(H,33,34)/t19-,21-,22-/m0/s1 InChIKey=RZRDCZDUYHBGDT-BVSLBCMMSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001
Additional Detail Fields 1 fields
3