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Peptide record

TPDB66682

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB66682
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors iDPPIV
Cardiometabolic peptides
Peptipedia iDPPIV
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors and iDPPIV) peptide sequence curated from Peptipedia and iDPPIV, with an available 3D structural model.
Sequence
VT
Physicochemical Analysis
C9H18N2O4
ARNDCEQGHILKMFPSWY
TV
218.25
6.02
0
0
1
-0
0.21
1.750
145.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
2
C9H18N2O4
218.25
6.02
-0
0.21
1.750
218.2495
218.1262
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O InChI=1S/C9H18N2O4/c1-4(2)6(10)8(13)11-7(5(3)12)9(14)15/h4-7,12H,10H2,1-3H3,(H,11,13)(H,14,15)/t5-,6+,7+/m1/s1 InChIKey=GVRKWABULJAONN-VQVTYTSYSA-N
Additional Detail Fields 1 fields
2