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Peptide record

TPDB66667

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66667
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VIRW
Physicochemical Analysis
C28H44N8O5
ANDCEQGHLKMFPSTY
RIWV
572.71
11.05
1
0
3
+1
-1.28
0.825
170.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5500
960.35
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
4
C28H44N8O5
572.71
11.05
+1
-1.28
0.825
572.6978
572.3425
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fan H., Wang J., Liao W., Jiang J., Wu J.
Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins. J. Agric. Food Chem., 67, 7147−7156, 2019
2019
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](C(C)C)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)O InChI=1S/C28H44N8O5/c1-5-16(4)23(36-25(38)22(29)15(2)3)26(39)34-20(11-8-12-32-28(30)31)24(37)35-21(27(40)41)13-17-14-33-19-10-7-6-9-18(17)19/h6-7,9-10,14-16,20-23,33H,5,8,11-13,29H2,1-4H3,(H,34,39)(H,35,37)(H,36,38)(H,40,41)(H4,30,31,32)/t16-,20-,21-,22-,23-/m0/s1 InChIKey=HZCFLBLVVZHPFX-DEKCZCQOSA-N
Additional Detail Fields 1 fields
4