Back to search

Peptide record

TPDB66664

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66664
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
VGPV
Physicochemical Analysis
C17H30N4O5
ARNDCEQHILKMFSTWY
V
370.45
6.02
0
0
2
-0
0.60
1.600
145.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
4
C17H30N4O5
370.45
6.02
-0
0.60
1.600
370.4427
370.2209
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fu Y, Young JF, Rasmussen MK, Dalsgaard TK, Lametsch R, Aluko RE, Therkildsen M.
Angiotensin I–converting enzyme–inhibitory peptides from bovine collagen: insights into inhibitory mechanism and transepithelial transport. Food Res. Int. 89, 373–381, 2016
2016
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](C(C)C)C(=O)NCC(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)O InChI=1S/C17H30N4O5/c1-9(2)13(18)16(24)19-8-12(22)21-7-5-6-11(21)15(23)20-14(10(3)4)17(25)26/h9-11,13-14H,5-8,18H2,1-4H3,(H,19,24)(H,20,23)(H,25,26)/t11-,13-,14-/m0/s1 InChIKey= WHFDCTYBJCLVAN-UBHSHLNASA-N
Additional Detail Fields 1 fields
4