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Peptide record

TPDB66649

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66649
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
TPYPCV
Physicochemical Analysis
C31H46N6O9S1
ARNDEQGHILKMFSW
P
678.80
5.32
0
0
2
-0
-0.07
0.250
48.33
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
219.50
3
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
6
C31H46N6O9S1
678.80
5.32
-0
-0.07
0.250
678.7960
678.3036
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
2.58 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Aiemratchanee P., Panyawechamontri K., Phaophu P., Reamtong O., Panbangred W.
In vitro antihypertensive activity of bioactive peptides derived from porcine blood corpuscle and plasma proteins. Int. J. Food Sci. Technol., 56, 2315–2324, 2021
2021
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H]([C@H](O)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N3[C@@H](CCC3)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)O InChI=1S/C31H46N6O9S/c1-16(2)25(31(45)46)35-26(40)21(15-47)34-28(42)22-6-4-12-36(22)29(43)20(14-18-8-10-19(39)11-9-18)33-27(41)23-7-5-13-37(23)30(44)24(32)17(3)38/h8-11,16-17,20-25,38-39,47H,4-7,12-15,32H2,1-3H3,(H,33,41)(H,34,42)(H,35,40)(H,45,46)/t17-,20+,21+,22+,23+,24+,25+/m1/s1 InChIKey=KBAHKBQROKPWCU-AGZZQPQKSA-N
Additional Detail Fields 1 fields
6