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Peptide record

TPDB66641

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB66641
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors iDPPIV
Cardiometabolic peptides
Peptipedia iDPPIV
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors and iDPPIV) peptide sequence curated from Peptipedia and iDPPIV, with an available 3D structural model.
Sequence
SW
Physicochemical Analysis
C14H17N3O4
ARNDCEQGHILKMFPTYV
SW
291.31
6.02
0
0
1
-0
-1.72
-0.850
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
1888.04
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
2
C14H17N3O4
291.31
6.02
-0
-1.72
-0.850
291.3018
291.1215
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CO)C(=O)N[C@@H](CC1=C[N]([H])C2=CC=CC=C12)C(=O)O InChI=1S/C14H17N3O4/c15-10(7-18)13(19)17-12(14(20)21)5-8-6-16-11-4-2-1-3-9(8)11/h1-4,6,10,12,16,18H,5,7,15H2,(H,17,19)(H,20,21)/t10-,12-/m0/s1 InChIKey=LZLREEUGSYITMX-JQWIXIFHSA-N Pancreatic lipase inhibitor according to the BIOPEP-UWM database of bioactive peptides
Additional Detail Fields 1 fields
2