Back to search

Peptide record

TPDB66638

ACE inhibitor ACE inhibitors standard
3 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66638
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
SLR
Physicochemical Analysis
C15H30N6O5
ANDCEQGHIKMFPTWYV
RLS
374.44
11.05
1
0
1
+1
0.38
-0.500
130.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C15H30N6O5
374.44
11.05
+1
0.38
-0.500
374.4347
374.2271
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
170.00 µM
Inhibitor of angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Lafarga T, Aluko RE, Rai DK, O'Connor P, Hayes M.
Identification of bioactive peptides from a papain hydrolysate of bovine serum albumin and assessment of an antihypertensive effect in spontaneously hypertensive rats. Food Res Int. 81, 91-99, 2016
2016
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI= 1S/C15H30N6O5/c1-8(2)6-11(21-12(23)9(16)7-22)13(24)20-10(14(25)26)4-3-5-19-15(17)18/h8-11,22H,3-7,16H2,1-2H3,(H,20,24)(H,21,23)(H,25,26)(H4,17,18,19)/t9-,10-,11-/m0/s1 InChIKey: QYSFWUIXDFJUDW-DCAQKATOSA-N
Additional Detail Fields 1 fields
3