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Peptide record

TPDB66624

ACE inhibitor ACE inhibitors standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB66624
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RVR
Physicochemical Analysis
C17H35N9O4
ANDCEQGHILKMFPSTWY
R
429.52
12.40
2
0
1
+2
1.69
-1.600
96.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
3
C17H35N9O4
429.52
12.40
+2
1.69
-1.600
429.5163
429.2805
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
526.00 µM
Inhibitor of angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Orio L. P., Boschin G., Recca, T., Morelli C. F., Ragona L., Francescato P., Arnoldi A., Speranza G.
New ACE-inhibitory peptides from hemp seed (Cannabis sativa L.) proteins. J. Agric. Food Chem.,65, 10482-10488, 2017
2017
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(N)=N)C(O)=O InChI=1S/C17H35N9O4/c1-9(2)12(26-13(27)10(18)5-3-7-23-16(19)20)14(28)25-11(15(29)30)6-4-8-24-17(21)22/h9-12H,3-8,18H2,1-2H3,(H,25,28)(H,26,27)(H,29,30)(H4,19,20,23)(H4,21,22,24)/t10-,11-,12-/m0/s1 InChIKey: ISVACHFCVRKIDG-SRVKXCTJSA-N
Additional Detail Fields 1 fields
3