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Peptide record

TPDB66621

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66621
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RVCLP
Physicochemical Analysis
C25H46N8O6S1
ANDEQGHIKMFSTWY
RCLPV
586.75
9.01
1
0
2
+1
0.53
0.880
136.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C25H46N8O6S1
586.75
9.01
+1
0.53
0.880
586.7470
586.3251
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
175.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Wu S., Feng X., Lan X., Xu Y., Liao D.
Purification and identification of Angiotensin-I Converting Enzyme (ACE) inhibitory peptide from lizard fish (Saurida elongata) hydrolysate. J. Funct. Foods, 13, 295-299 (2015)
2015
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C25H46N8O6S/c1-13(2)11-16(23(37)33-10-6-8-18(33)24(38)39)30-21(35)17(12-40)31-22(36)19(14(3)4)32-20(34)15(26)7-5-9-29-25(27)28/h13-19,40H,5-12,26H2,1-4H3,(H,30,35)(H,31,36)(H,32,34)(H,38,39)(H4,27,28,29)/t15-,16-,17-,18-,19-/m0/s1 InChIKey: BIYLPYGMGOUNEQ-VMXHOPILSA-N
Additional Detail Fields 1 fields
5